Diaminomaleonitrile → HCID 54464277, 화합물

HRID 1031162노트

반응식

[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([Cl:12])[C:3]=1[N:13]1[N:17]=[C:16]([CH2:18][CH:19]=O)[C:15]([CH3:21])=[N:14]1.[NH2:22]/[C:23](/[C:28]#[N:29])=[C:24](\[NH2:27])/[C:25]#[N:26]>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([Cl:12])[C:3]=1[N:13]1[N:17]=[C:16]([CH2:18][CH:19]=[N:22][C:23]([C:28]#[N:29])=[C:24]([NH2:27])[C:25]#[N:26])[C:15]([CH3:21])=[N:14]1

참가 물질

반응물 2

HCID 2723951Diaminomaleonitrile

HCID 53721970HCID 53721970, 화합물

생성물 1

HCID 54464277HCID 54464277, 화합물

실험 절차

2-(2,6-Dichloro-4-trifluoromethylphenyl)-5-methyl-2H-1,2,3-triazole-4-acetaldehyde was treated with diaminomaleonitrile in a similar manner to Example 1, to give 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-[2-(2-amino-1,2-dicyanoethenylimino)ethyl]-5-methyl-2H-1,2,3-triazole, which was cyclised in a similar manner to Example 1a, to give 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-[(4,5-dicyano-1H-imidazol-2-yl)methyl]-5-methyl-2H-1,2,3-triazole (Compound 33).

출처 및 근거

ORD 기록: ord-3dd28e95683e4ce2aeabb390927aded8
출처 데이터셋: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05109012

반응 노트

불러오는 중…