1,6-Dibromohexane → 1-[2-[(6-Bromohexyl)oxy]ethyl]naphthalene

반응식

[C:1]1([CH2:11][CH2:12][OH:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[Br:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]Br>>[Br:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][O:13][CH2:12][CH2:11][C:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

참가 물질

반응물 2

HCID 123681,6-Dibromohexane

HCID 13047Naphthalen-1-ethanol

생성물 1

HCID 191018371-[2-[(6-Bromohexyl)oxy]ethyl]naphthalene수율 74%

실험 절차

1-Naphthaleneethanol (3.00 g) and 1,6-dibromohexane (12.73 g) were treated according to the method of Intermediate 1. FCC eluting with cyclohexane followed by ethyl acetate-cyclohexane (1:20, then 1:4) gave the title compound (4.32 g) as a colourless oil.

후처리

washFCC eluting with cyclohexane

출처 및 근거

ORD 기록: ord-38f2332512f044ca9dbc5dc2069f028e
출처 데이터셋: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05109023

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