3-Iodomethyl-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester → 3-[2-(4-Chloro-phenyl)-pyrimidin-5-yloxymethyl]-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester

HRID 103229

반응식

HRID 103229 반응식
[CH2:15]([CH3:16])[O:17][C:18](=[O:19])[C:20]1([CH2:35][I:36])[CH2:21][N:22]([C:25]([c:26]2[c:27]([O:32][CH3:33])[cH:28][cH:29][cH:30][cH:31]2)=[O:34])[CH2:23][CH2:24]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([OH:14])[cH:12][n:13]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([O:14][CH2:35][C:20]3([C:18]([O:17][CH2:15][CH3:16])=[O:19])[CH2:21][N:22]([C:25]([c:26]4[c:27]([O:32][CH3:33])[cH:28][cH:29][cH:30][cH:31]4)=[O:34])[CH2:23][CH2:24]3)[cH:12][n:13]2)[cH:6][cH:7]1

참가 물질

3

반응물 2

HCID 593221723-Iodomethyl-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl esterHCID 593221782-(4-Chlorophenyl)pyrimidin-5-ol

생성물 1

HCID 593222323-[2-(4-Chloro-phenyl)-pyrimidin-5-yloxymethyl]-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester

출처 및 근거

ORD 기록
ord-4468f821ede84cb1a7ab246661992281
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

연결된 노트

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