Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl Peroxide → 2-(Bromomethyl)-5-chlorobenzo[d]oxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | 5-Chloro-2-methylbenzoxazole | HCID 29510 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 2-(Bromomethyl)-5-chlorobenzo[d]oxazole | HCID 12745945 | — |
반응 단계
A solution of the benzoxazole (1.3 g) (Step 2) in CCl4 (15 mL) was treated with N-bromo-succinimide (NBS) (1.5 g) and benzoyl peroxide (38 mg) at reflux using a U.V. lamp for 24 hours. Filtration, evaporation, and flash chromatography of the residue using 1:1 hexane/toluene afforded the title compound which was used as such for the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04957932 |
| 출처 데이터셋 | uspto-grants-1990_09 |
| ORD ID | ord-c8a92444ed334775971a2479e214d719 |
| 출처 메모 | uspto-grants-1990_09 |