2-Methoxy-3-nitro-5-ethyl-6-methylpyridine → 2-Methoxy-3-amino-5-ethyl-6-methylpyridine
반응식
[CH3:1][O:2][C:3]1[C:8]([N+:9]([O-])=O)=[CH:7][C:6]([CH2:12][CH3:13])=[C:5]([CH3:14])[N:4]=1>CO.O1CCCC1.[Pd]>[CH3:1][O:2][C:3]1[C:8]([NH2:9])=[CH:7][C:6]([CH2:12][CH3:13])=[C:5]([CH3:14])[N:4]=1참가 물질
5
실험 절차
A solution of 2-methoxy-3-nitro-5-ethyl-6-methylpyridine (535 mg, 2.72 mmol) in methanol (8 mL) and tetrahydrofuran (8 mL) containing 5% palladium on carbon (83 mg) was hydrogenated at atmospheric pressure for 5 hours. The catalyst was filtered off the solvent evaporated to yield 436 mg (98%) of oily product.
후처리
- filtrationThe catalyst was filtered off the solvent
- customevaporated
출처 및 근거
- ORD 기록
- ord-43607c74710f483782df876a5943b4f2
- 출처 데이터셋
- uspto-grants-1994_05
- 특허 번호
- US05308854
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