Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → Diethyl 1-hexyl-2,5-dioxo-4-imidazolylphosphonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-Iodohexane | HCID 12527 | — |
| 반응물 | Diethyl (2,5-dioxo-2,5-dihydro-1H-imidazol-4-yl)phosphonate | HCID 53733419 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Diethyl 1-hexyl-2,5-dioxo-4-imidazolylphosphonate | HCID 53646860 | — |
반응 단계
To a solution of diethyl 2,5-dioxo-4-imidazolylphosphonate (6.00 g, 0.025 moles) in DMF (15 mL), under N2, is added K2CO3 (17.5 g, 0.127 moles) and 1-iodohexane (3.75 mL, 0.025 moles). This mixture is stirred at room temperature for 16 hours. The mixture is diluted with ether (300 mL) and washed with water and brine and then dried over MgSO4. Evaporation of solvents under high vacuum affords the required product as a viscous yellow oil. (Mass spectrometry also revealed a small amount of diethyl 1,3-dihexyl-2,5-dioxo-4-imidazolylphosphonate).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05308853 |
| 출처 데이터셋 | uspto-grants-1994_05 |
| ORD ID | ord-e171d2619a6f4e12831c6f542031fa3d |
| 출처 메모 | uspto-grants-1994_05 |