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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1033303생성일: 2026년 10월 27일

Sodium borohydride → (2R*,4S*)-2-benzyl-1-(3,5-dichlorobenzoyl)-N-(4-quinolylmethyl)-4-piperidinamine

https://huagongshe.com/reaction/1033303

반응식

참여 물질

역할이름HCID투입량
반응물Sodium borohydrideHCID 4311764—
반응물(2R*,4S*)-2-benzyl-1-(3,5-dichlorobenzoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamineHCID 44288934—
생성물(2R*,4S*)-2-benzyl-1-(3,5-dichlorobenzoyl)-N-(4-quinolylmethyl)-4-piperidinamineHCID 44288927—

반응 단계

1.21 g (2.01 mmol) of (2R*,4S*)-2-benzyl-1-(3,5-dichlorobenzoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine are reacted with 0.305 mg (8.06 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR33## is obtained as white foam; TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.37; FD-MS: M+ =503.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05310743
출처 데이터셋uspto-grants-1994_05
ORD IDord-287669f8d59c4441b222dde60ee5f862
출처 메모uspto-grants-1994_05