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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1033352생성일: 2026년 10월 26일

Trifluoroacetic acid → (2R*,4S*)-2-Benzyl-N-(2-phenylethyl)-N-trifluoroacetyl-4-piperidinamine

https://huagongshe.com/reaction/1033352

반응식

참여 물질

역할이름HCID투입량
반응물Trifluoroacetic acidHCID 6422—
반응물(2R*,4S*)-2-Benzyl-1-t-butyloxycarbonyl-N-(2-phenylethyl)-N-trifluoroacetyl-4-piperidinamineHCID 57018205—
생성물(2R*,4S*)-2-Benzyl-N-(2-phenylethyl)-N-trifluoroacetyl-4-piperidinamineHCID 22863105—

반응 단계

615 mg (1.25 mmol) of (2R*,4S*)-2-benzyl-1-t-butyloxycarbonyl-N-(2-phenylethyl)-N-trifluoroacetyl-4-piperidinamine are reacted with 1.9 ml (25 mmol) of trifluoroacetic acid in analogy to Example 38d. The title compound is obtained as oil (308 mg, 63%). TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.63, FD-MS: M+ =390.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05310743
출처 데이터셋uspto-grants-1994_05
ORD IDord-5ae966b8fa1b4a05912c26d89f22e29e
출처 메모uspto-grants-1994_05