Water → 145486-31-3

HRID 1033431노트

반응식

HRID 1033431 반응식
O.[CH2:2]([O:9][C:10]([CH3:14])([CH:12]=C)[CH3:11])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.I([O-])(=O)(=O)=[O:16].[Na+]>[Os](=O)(=O)(=O)=O.O1CCOCC1>[CH2:2]([O:9][C:10]([CH3:11])([CH3:14])[CH:12]=[O:16])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

참가 물질

6

반응물 3

HCID 962WaterHCID 10487510HCID 10487510, 화합물HCID 23667635Sodium periodate

생성물 1

HCID 10986836145486-31-3수율 37%

시약·촉매·용매 2

HCID 30318Osmium Tetroxide촉매HCID 312751,4-Dioxane용매

실험 절차

A mixture of 100 mL of water, 200 mL of dioxane, 20 g (0.11 mol) of 2-benzyloxy-2-methyl-3-butene and 1 g of osmium tetroxide was stirred at room temperature for 30 minutes then 51 g (0.22 mol) of finely ground sodium periodate was added in portions over 30 minutes. Stirring was continued for 2 hours then the mixture filtered and the filtrate extracted with several portions of ether. The combined extracts were dried over magnesium sulfate, filtered and the filtrate concentrated under vacuum. Distillation afforded 7.3 g (0.041 mol, 37%) of product, b.p. 85°-88° C. (2 mm).

후처리

  1. stirringStirring
  2. waitwas continued for 2 hours
  3. filtrationthe mixture filtered
  4. extractionthe filtrate extracted with several portions of ether
  5. dry with materialThe combined extracts were dried over magnesium sulfate
  6. filtrationfiltered
  7. concentrationthe filtrate concentrated under vacuum
  8. distillationDistillation

출처 및 근거

ORD 기록
ord-86bbd5393f244782978e3326ac084cc1
출처 데이터셋
uspto-grants-1994_05
특허 번호
US05310737

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