Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3'-Chloro-4'-octyloxy-4-biphenylcarboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Dichloramine-T | HCID 68056 | — |
| 반응물 | 4'-(Octyloxy)-[1,1'-biphenyl]-4-carboxylic acid | HCID 2802556 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 3'-Chloro-4'-octyloxy-4-biphenylcarboxylic acid | HCID 14794181 | 128.2% |
반응 단계
N,N-dichloro-p-toluenesulfonamide (hereinafter abbreviated to "dichloramine T") (7.5 g, 0.032 mol) was dissolved in acetic acid (100 ml), followed by adding to the solution, hydrochloric acid (0.4 ml), dropwise adding to the acetic acid solution of dichloramine T, a solution of 4'-octyloxy-4-biphenylcarboxylic acid (20 g, 0.063 mol) dissolved in acetic acid (100 ml), refluxing the mixture, allowing it to stand overnight, distilling off acetic acid and filtering off deposited crystals to obtain 3'-chloro-4'-octyloxy-4-biphenylcarboxylic acid (14.8 g) (C-Sc 146° C., Sc '-N' 224° C. and N'-I 232° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05312564 |
| 출처 데이터셋 | uspto-grants-1994_05 |
| ORD ID | ord-efebf27abd834d94a66ef657ccdc98b9 |
| 출처 메모 | uspto-grants-1994_05 |