Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-Chloro-4-hydroxy-benzoic acid 2-methyl-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Dichloramine-T | HCID 68056 | — |
| 반응물 | Benzoic acid, 4-hydroxy-, 2-methylbutyl ester | HCID 13530949 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 3-Chloro-4-hydroxy-benzoic acid 2-methyl-butyl ester | HCID 23041682 | 144.2% |
반응 단계
On the other hand, dichloramine T (28.0 g, 0.12 mol) was dissolved in acetic acid (450 ml), and hydrochloric acid (1.5 ml) was added. The resulting solution was dropwise added to a solution of the above p-hydroxybenzoic acid 2-methyl-butyl ester (50 g, 0.24 mol) dissolved in acetic acid (450 ml), followed by refluxing the mixture, allowing to stand overnight, distilling off acetic acid and filtering off deposited crystals to obtain 3-chloro-4-hydroxy-benzoic acid 2-methyl-butyl ester (42 g) (b.p. 135°~138° C./4 mmHg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05312564 |
| 출처 데이터셋 | uspto-grants-1994_05 |
| ORD ID | ord-9628d6e533e344f2897cf7d0226e1cb9 |
| 출처 메모 | uspto-grants-1994_05 |