4-Methoxybenzyl alcohol → p-Methoxybenzyl acrylate

HRID 1033900

반응식

HRID 1033900 반응식
C(C1N(CC2C=CC=CC=2Cl)[C:7](/C=C(\CC2C=CC=CC=2)/C(O)=O)=[C:8]([CH2:10][OH:11])N=1)CCC.[CH3:32][O:33][C:34]1[CH:41]=[CH:40][C:37]([CH2:38][OH:39])=[CH:36][CH:35]=1>>[C:10]([O:39][CH2:38][C:37]1[CH:40]=[CH:41][C:34]([O:33][CH3:32])=[CH:35][CH:36]=1)(=[O:11])[CH:8]=[CH2:7]

참가 물질

3

반응물 2

HCID 77384-Methoxybenzyl alcoholHCID 67849088HCID 67849088, 화합물

생성물 1

HCID 346146p-Methoxybenzyl acrylate

실험 절차

(E)-3-[2-n-Butyl-1-[(2-chlorophenyl)methyl]-4-hydroxymethyl-1H-imidazol-5-yl]-2-benzyl-2-propenoic acid, prepared as in Example 28, is esterified with p-methoxy-benzyl alcohol to give the p-methoxybenzyl propenoate. The 4-hydroxymethyl group is oxidized using Jones reagent in acetone and the ester is hydrolized using 10% sodium hydroxide to give the title compound.

출처 및 근거

ORD 기록
ord-b7e90e03d6104bf2b332356eb5d5c5b1
출처 데이터셋
uspto-grants-1994_05
특허 번호
US05312828

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