3-Ethoxy-4-ethoxycarbonylphenylacetic acid → Ethyl 2-ethoxy-4-[N-(5-chloro-2-piperidino-benzyl)-aminocarbonylmethyl]benzoate

반응식

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)=[C:6]([CH:9]=1)[CH2:7][NH2:8].[CH2:16]([O:18][C:19]1[CH:20]=[C:21]([CH2:30][C:31](O)=[O:32])[CH:22]=[CH:23][C:24]=1[C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH3:17]>>[CH2:16]([O:18][C:19]1[CH:20]=[C:21]([CH2:30][C:31]([NH:8][CH2:7][C:6]2[CH:9]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=2[N:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)=[O:32])[CH:22]=[CH:23][C:24]=1[C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH3:17]

참가 물질

반응물 2

HCID 101312123-Ethoxy-4-ethoxycarbonylphenylacetic acid

HCID 105611475-Chloro-2-piperidino-benzylamine

생성물 1

HCID 21261760Ethyl 2-ethoxy-4-[N-(5-chloro-2-piperidino-benzyl)-aminocarbonylmethyl]benzoate

실험 절차

Prepared from 5-chloro-2-piperidino-benzylamine and 3-ethoxy-4-ethoxycarbonyl-phenylacetic acid.

출처 및 근거

ORD 기록: ord-6b71c9e846be478dbf22ade279705f63
출처 데이터셋: uspto-grants-1994_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05312924

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