Ethyl 4-(hydroxyimino)-5-oxo-1-phenyl-3-pyrrolidineacetate → Ethyl 4-amino-5-oxo-1-phenyl-3-pyrrolidineacetate
반응식
O[N:2]=[C:3]1[C:7](=[O:8])[N:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:5][CH:4]1[CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]>CCO.[Pd]>[NH2:2][CH:3]1[C:7](=[O:8])[N:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:5][CH:4]1[CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]참가 물질
4
실험 절차
A solution of the product of example 63 in EtOH is hydrogenated with 10% palladium on carbon at 60 psi at 60° C. Filtration and purification of the product on silica gel affords the title compound.
후처리
- filtrationFiltration and purification of the product on silica gel
출처 및 근거
- ORD 기록
- ord-f6428ceea59541f69d5d9979113c4bc9
- 출처 데이터셋
- uspto-grants-1994_05
- 특허 번호
- US05314886
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