Potassium Hydroxide → HCID 178418656, 화합물
반응식
C([O:3][C:4](=[S:18])[CH:5]([CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:6][C:7]([CH3:10])([CH3:9])[CH3:8])C.[OH-].[K+]>CO>[CH2:11]([CH:5]([CH2:6][C:7]([CH3:10])([CH3:9])[CH3:8])[C:4]([OH:3])=[S:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1참가 물질
4
실험 절차
400 mg of 2-benzyl-3-tert.-butylthio-propionic acid ethyl ester was dissolved in 1.5 ml of methanol and then reacted with 5 ml of 2N potassium hydroxide solution. The mixture was stirred at room temperature overnight and concentrated by evaporation. The residue was diluted with water and washed with ether. The aqueous layer was acidified to pH 3 with 2N HCl, and then evaporated to give the title compound (280 mg, 78% yield). 1H NMR: 300 MHz spectrum consistent with proposed structure.
후처리
- concentrationconcentrated by evaporation
- additionThe residue was diluted with water
- washwashed with ether
- customevaporated
출처 및 근거
- ORD 기록
- ord-50df2e9d63e640618ba40bf91c113995
- 출처 데이터셋
- uspto-grants-1994_05
- 특허 번호
- US05314920
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