8-Bromo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine → HCID 9881885, 화합물

HRID 1035327노트

반응식

HRID 1035327 반응식
Cl[C:2]1[C:3]([O:14][CH3:15])=[CH:4][C:5]2[CH2:11][CH2:10][NH:9][CH2:8][CH:7]([CH3:12])[C:6]=2[CH:13]=1.IC1C(OC)=CC2CCNCC(C)C=2C=1.CN1CC(C)C2C=C([Br:46])C(OC)=CC=2CC1.BrC1C(OC)=CC2CCNCC(CC)C=2C=1.ClC1C(OC)=CC2CCNCC(CC)C=2C=1.IC1C(OC)=CC2CCNCC(CC)C=2C=1.COC1C(C(F)(F)F)=CC2C(C)CNCCC=2C=1.COC1C(C(F)(F)C(F)(F)F)=CC2C(C)CNCCC=2C=1>>[Br:46][C:2]1[C:3]([O:14][CH3:15])=[CH:4][C:5]2[CH2:11][CH2:10][NH:9][CH2:8][CH:7]([CH3:12])[C:6]=2[CH:13]=1

참가 물질

9

반응물 8

HCID 99940088-Bromo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 100154147-Methoxy-1-methyl-8-trifluoromethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 100366298-Chloro-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 100601798-Chloro-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepineHCID 100643867-iodo-8-methoxy-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepineHCID 10085262N-Methyl-8-bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepineHCID 10314616HCID 10314616, 화합물HCID 104254257-Methoxy-1-methyl-8-pentafluoroethyl-2,3,4,5-tetrahydro-1H-3-benzazepine

생성물 1

HCID 9881885HCID 9881885, 화합물

실험 절차

8-Chloro-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; 8-Iodo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; N-Methyl-8-bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; 8-Bromo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine; 8-Chloro-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine; 8-Iodo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine; 7-Methoxy-1-methyl-8-trifluoromethyl-2,3,4,5-tetrahydro-1H-3-benzazepine; and 7-Methoxy-1-methyl-8-pentafluoroethyl-2,3,4,5-tetrahydro-1H-3-benzazepine; or a pharmaceutically acceptable salt, solvate or hydrate thereof.

출처 및 근거

ORD 기록
ord-19a05e945761447a945c5855c45f9d36
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08546379B2

반응 노트

불러오는 중…