3-tert-Butylbenzoyl chloride → 3-tert-butyl-N-(3-(2-methyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy) phenyl)benzamide
반응식
[NH2:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][CH:20]=1)[O:5][C:6]1[C:15]2[N:14]=[C:13]([CH3:16])[C:12](=[O:17])[NH:11][C:10]=2[N:9]=[CH:8][CH:7]=1.[C:21]([C:25]1[CH:26]=[C:27]([CH:31]=[CH:32][CH:33]=1)[C:28](Cl)=[O:29])([CH3:24])([CH3:23])[CH3:22]>>[C:21]([C:25]1[CH:26]=[C:27]([CH:31]=[CH:32][CH:33]=1)[C:28]([NH:1][C:2]1[CH:20]=[CH:19][CH:18]=[C:4]([O:5][C:6]2[C:15]3[N:14]=[C:13]([CH3:16])[C:12](=[O:17])[NH:11][C:10]=3[N:9]=[CH:8][CH:7]=2)[CH:3]=1)=[O:29])([CH3:24])([CH3:22])[CH3:23]참가 물질
3
실험 절차
Method G1 was used with 8-(3-aminophenoxy)-2-methylpyrido[2,3-b]pyrazin-3(4H)-one and 3-tertbutylbenzoyl chloride to afford the title compound as a slightly yellow solid (77 mg, 97%).
출처 및 근거
- ORD 기록
- ord-9cda407c65114e929114d56a0ae2ade3
- 출처 데이터셋
- uspto-grants-2013_10