2-Bromo-6-methoxynaphthalene → 2-Methoxy-6-(4-methoxyphenyl)naphthalene

HRID 1035600노트

반응식

HRID 1035600 반응식
Br[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([O:12][CH3:13])[CH:8]=2)[CH:3]=1.[CH3:14][O:15][C:16]1[CH:21]=[CH:20][C:19](OB(O)O)=[CH:18][CH:17]=1>>[CH3:13][O:12][C:7]1[CH:6]=[CH:5][C:4]2[C:9](=[CH:10][CH:11]=[C:2]([C:19]3[CH:20]=[CH:21][C:16]([O:15][CH3:14])=[CH:17][CH:18]=3)[CH:3]=2)[CH:8]=1

참가 물질

3

반응물 2

HCID 787862-Bromo-6-methoxynaphthaleneHCID 147699944-Methoxyphenyl boric acid

생성물 1

HCID 111497342-Methoxy-6-(4-methoxyphenyl)naphthalene수율 56%

실험 절차

The compound is prepared by the reaction of 2-bromo-6-methoxynaphthalene (500 mg, 2.11 mmol, 1 eq) with 4-methoxyphenylboric acid (313 mg, 2.12 mmol, 1 eq) according to method A in 5 h. The desired product was precipitated from hexane in a yield of 56% (311 mg).

후처리

  1. customThe desired product was precipitated from hexane in a yield of 56% (311 mg)

출처 및 근거

ORD 기록
ord-d5b24212f965472aa7aa059a5de8cdb2
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08546392B2

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