Methylamine → HCID 59443449, 화합물

HRID 1035632노트

반응식

HRID 1035632 반응식
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)[CH:9]=2)[C:4]=1[C:21]([OH:23])=O.[CH3:24][NH2:25]>>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)[CH:9]=2)[C:4]=1[C:21]([NH:25][CH3:24])=[O:23]

참가 물질

3

반응물 2

HCID 6329MethylamineHCID 594434812-Methoxy-6-(3-methoxyphenyl)-1-naphthoic acid

생성물 1

HCID 59443449HCID 59443449, 화합물

실험 절차

The compound was prepared by reaction of 2-methoxy-6-(3-methoxyphenyl)-1-naphthoic acid (300 mg, 0.97 mmol, 1 eq) with 33% methylamine (1 eq) according to method D. Purification by column chromatography was not necessary. The desired compound was obtained in quantitative yield (311 mg).

후처리

  1. customPurification by column chromatography

출처 및 근거

ORD 기록
ord-6a091a732e494de3b181d9abef7595bc
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08546392B2

반응 노트

불러오는 중…