Trifluoroacetic acid → Trifluoroacetic acid
반응식
CC(OC([NH:8][CH2:9][CH:10]1[CH2:15][CH2:14][CH:13]([OH:16])[CH2:12][CH2:11]1)=O)(C)C.[F:17][C:18]([F:23])([F:22])[C:19]([OH:21])=[O:20]>ClCCl>[NH2:8][CH2:9][C@H:10]1[CH2:15][CH2:14][C@H:13]([OH:16])[CH2:12][CH2:11]1.[F:17][C:18]([F:23])([F:22])[C:19]([OH:21])=[O:20]참가 물질
5
실험 절차
Tert-butyl ((1r,4r)-4-hydroxycyclohexyl)methylcarbamate (1 g) in dichloromethane (10 mL) was treated with trifluoroacetic acid (5 mL) at 0° C. for 10 minutes and at room temperature for 30 minutes. The reaction mixture was concentrated and dried in vacuo to provide the title compound as a trifluoroacetic acid salt.
후처리
- concentrationThe reaction mixture was concentrated
- customdried in vacuo
출처 및 근거
- ORD 기록
- ord-59005952259743b0837205f4d592e46b
- 출처 데이터셋
- uspto-grants-2013_10
- 특허 번호
- US08546399B2
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