Tert-butyl 5-(6-hydroxynaphthalen-2-yl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate → HCID 178452577, 화합물

HRID 1036417

반응식

HRID 1036417 반응식
[C:1]([C@@H:5]1[CH2:10][CH2:9][C@H:8]([OH:11])[CH2:7][CH2:6]1)([CH3:4])([CH3:3])[CH3:2].[C:12]([O:16][C:17](=[O:38])[NH:18][C:19]1([C:27]2[CH:36]=[CH:35][C:34]3[C:29](=[CH:30][CH:31]=[C:32](O)[CH:33]=3)[CH:28]=2)[CH2:24][O:23][C:22]([CH3:26])([CH3:25])[O:21][CH2:20]1)([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17](=[O:38])[NH:18][C:19]1([C:27]2[CH:36]=[CH:35][C:34]3[C:29](=[CH:30][CH:31]=[C:32]([O:11][C@H:8]4[CH2:7][CH2:6][C@H:5]([C:1]([CH3:4])([CH3:2])[CH3:3])[CH2:10][CH2:9]4)[CH:33]=3)[CH:28]=2)[CH2:20][O:21][C:22]([CH3:26])([CH3:25])[O:23][CH2:24]1)([CH3:13])([CH3:14])[CH3:15]

참가 물질

3

반응물 2

HCID 44228963Tert-butyl 5-(6-hydroxynaphthalen-2-yl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamateHCID 178445811HCID 178445811, 화합물

생성물 1

HCID 178452577HCID 178452577, 화합물수율 42%

실험 절차

The title compound was prepared from cis-4-tertbutylcyclohexanol and [5-[6-hydroxynaphthalen-2-yl)-2,2-dimethyl-1,3-dioxinan-5-yl]-carbamic acid tert-butyl ester in 42% yield according to the method of Example 53.

출처 및 근거

ORD 기록
ord-1a2061bcc3b942dd9a7eacffab1b2b8d
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08546359B2

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