1H-Indazole, 3-(4-morpholinyl)-5-nitro- → 3-Morpholino-1H-indazol-5-amine

HRID 1037994노트

반응식

HRID 1037994 반응식
[N:1]1([C:7]2[C:15]3[C:10](=[CH:11][CH:12]=[C:13]([N+:16]([O-])=O)[CH:14]=3)[NH:9][N:8]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1>CO.[H][H]>[N:1]1([C:7]2[C:15]3[C:10](=[CH:11][CH:12]=[C:13]([NH2:16])[CH:14]=3)[NH:9][N:8]=2)[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1

참가 물질

4

반응물 1

HCID 30513261H-Indazole, 3-(4-morpholinyl)-5-nitro-

생성물 1

HCID 30798583-Morpholino-1H-indazol-5-amine

시약·촉매·용매 2

HCID 178418361HCID 178418361, 화합물촉매HCID 887Methanol용매

실험 절차

3-Morpholin-4-yl-5-nitro-1H-indazole (210 mg) was dissolved in 10 ml of methanol and the mixture hydrogenated at 1 atm of hydrogen using 10% Pd/C (50 mg) as catalyst. After 24 hrs, the mixture was filtered and evaporated for use in the next step.

후처리

  1. filtrationthe mixture was filtered
  2. customevaporated for use in the next step

출처 및 근거

ORD 기록
ord-cae09478cbda4e4582b5f19178b28be9
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08546404B2

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