N,N-dimethyl-m-phenylenediamine → HCID 66670065, 화합물

반응식

Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][CH3:9])[CH:3]=1.[CH3:10][N:11]([CH3:19])[C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([NH2:18])[CH:13]=1>>[CH3:10][N:11]([CH3:19])[C:12]1[CH:13]=[C:14]([NH:18][C:2]2[CH:3]=[C:4]([NH:8][CH3:9])[N:5]=[CH:6][N:7]=2)[CH:15]=[CH:16][CH:17]=1

참가 물질

반응물 2

HCID 76084N,N-dimethyl-m-phenylenediamine

HCID 3094796-chloro-N-methylpyrimidin-4-amine

생성물 1

HCID 66670065HCID 66670065, 화합물

실험 절차

The title compound is prepared analogously as described in Example 105A from (6-chloro-pyrimidin-4-yl)-methylamine and N,N-dimethyl-m-phenylenediamine. The crude product obtained after evaporation of the ethyl acetate layer is purified by flash chromatography (CH2Cl2/CH3OH).

출처 및 근거

ORD 기록: ord-22968072f82548bab1670855f6e41894
출처 데이터셋: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08552002B2

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