2-Isocyanato-1,4-dimethoxybenzene → 1-[6-(3-Chloro-phenylamino)-pyrimidin-4-yl]-3-(2,5-dimethoxy-phenyl)-urea

HRID 1038706노트

반응식

HRID 1038706 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[CH:14]=[C:13]([NH2:15])[N:12]=[CH:11][N:10]=2)[CH:5]=[CH:6][CH:7]=1.[CH3:16][O:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][C:19]=1[N:26]=[C:27]=[O:28]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[N:10]=[CH:11][N:12]=[C:13]([NH:15][C:27]([NH:26][C:19]3[CH:20]=[C:21]([O:24][CH3:25])[CH:22]=[CH:23][C:18]=3[O:17][CH3:16])=[O:28])[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 41784252-Isocyanato-1,4-dimethoxybenzeneHCID 66669982N~4~-(3-chlorophenyl)pyrimidine-4,6-diamine

생성물 1

HCID 577103331-[6-(3-Chloro-phenylamino)-pyrimidin-4-yl]-3-(2,5-dimethoxy-phenyl)-urea

실험 절차

The title compound is prepared analogously as described in Example 127 from N-(3-chloro-phenyl)-pyrimidine-4,6-diamine and 2,5-dimethoxyphenyl isocyanate.

출처 및 근거

ORD 기록
ord-009f666d9cb847e6b1cafefef63c6a21
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08552002B2

반응 노트

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