Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isatoic Anhydride → 2-amino-N-(pyridin-2-yl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isatoic Anhydride | HCID 8359 | — |
| 반응물 | 2-Aminopyridine | HCID 10439 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-amino-N-(pyridin-2-yl)benzamide | HCID 276325 | 54% |
반응 단계
A mixture of isatoic anhydride 71 (8.7 g, 0.053 mol) and 2-aminopyridine (5 g, 0.06 mol) was heated in dioxane (30 mL) for 6-7 hours. After cooling, the solvent was evaporated in vacuo, the residue treated with water and recrystallized from EtOH/H2O to yield 72 (6 g, 54%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08552009B2 |
| 출처 데이터셋 | uspto-grants-2013_10 |
| ORD ID | ord-a4ba31314b7b40a2a3232c4beaa6d4cc |
| 출처 메모 | uspto-grants-2013_10 |