3-Bromo-2-fluoro-5-methylpyridine → HCID 56655688, 화합물

HRID 1039005

반응식

HRID 1039005 반응식
[F:1][C:2]([F:22])([F:21])[O:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:14][CH2:13][C:12]3([CH2:19][CH2:18][NH:17][CH2:16][CH2:15]3)[C:11]2=[O:20])=[CH:6][CH:5]=1.Br[C:24]1[C:25]([F:31])=[N:26][CH:27]=[C:28]([CH3:30])[CH:29]=1>>[F:31][C:25]1[C:24]([N:17]2[CH2:16][CH2:15][C:12]3([C:11](=[O:20])[N:10]([C:7]4[CH:8]=[CH:9][C:4]([O:3][C:2]([F:1])([F:21])[F:22])=[CH:5][CH:6]=4)[CH2:14][CH2:13]3)[CH2:19][CH2:18]2)=[CH:29][C:28]([CH3:30])=[CH:27][N:26]=1

참가 물질

3

반응물 2

HCID 218165633-Bromo-2-fluoro-5-methylpyridineHCID 667427592-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-one

생성물 1

HCID 56655688HCID 56655688, 화합물

실험 절차

The title compound was prepared in analogy to example 1 step D from a mixture of 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one (described in example 1 step C) and 3-bromo-2-fluoro-5-methylpyridine. Light yellow solid. MS (ESI): 424.1 (MH+)

출처 및 근거

ORD 기록
ord-d3524c3bf54e48c0860a59de9fdffb56
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08552024B2

연결된 노트

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