참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | Piperidin-4-ol | HCID 79341 | — |
| 반응물 | O-methyl hydrazinecarbothioate | HCID 10171237 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-Hydrazinothiocarbonylpiperidin-4-ol | HCID 55281286 | — |
반응 단계
A solution of methyl hydrazinecarbothioate (1.0 g, 8.2 mmol) and piperidin-4-ol (1.24 g, 12.3 mmol) in ethanol (7 mL) was refluxed with heating at 90° C. for 2 days. After addition of ethyl acetate, the reaction solution was washed with saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate and concentrated to give the crude desired product. The crude product was used directly for the next reaction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08552031B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_10 |
|---|
| ORD ID | ord-ffdf41338bfb4baf90c4987ed35a4d2c |
|---|
| 출처 메모 | uspto-grants-2013_10 |
|---|
