Sodium Carbonate → (1S,4R)-4-hydroxy-2,2-dimethyl-4-{5-[3-methyl-5-(4-methyl-pyrimidin-2-ylamino)-phenyl]-1,3-thiazol-2-yl}-cyclohexanecarboxylic acid methyl ester

반응식

[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:14]=[C:13](B3OC(C)(C)C(C)(C)O3)[CH:12]=[C:11]([CH3:24])[CH:10]=2)[N:3]=1.[CH3:25][O:26][C:27]([C@H:29]1[CH2:34][CH2:33][C@@:32]([C:36]2[S:37][C:38](Br)=[CH:39][N:40]=2)([OH:35])[CH2:31][C:30]1([CH3:43])[CH3:42])=[O:28].C(=O)([O-])[O-].[Na+].[Na+]>CC1CCCO1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>[CH3:25][O:26][C:27]([C@H:29]1[CH2:34][CH2:33][C@:32]([OH:35])([C:36]2[S:37][C:38]([C:13]3[CH:14]=[C:9]([NH:8][C:4]4[N:3]=[C:2]([CH3:1])[CH:7]=[CH:6][N:5]=4)[CH:10]=[C:11]([CH3:24])[CH:12]=3)=[CH:39][N:40]=2)[CH2:31][C:30]1([CH3:43])[CH3:42])=[O:28]