Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-((tert-Butoxycarbonyl)amino)cyclopropanecarboxylic acid → tert-butyl N-(1-cyanocyclopropyl)carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-((tert-Butoxycarbonyl)amino)cyclopropanecarboxylic acid | HCID 688396 | — |
| 반응물 | [1-(N-Hydroxy-carbamimidoyl)-cyclopropyl]-carbamic acid tert-butyl ester | HCID 178452922 | — |
| 반응물 | HCID 178458070 | HCID 178458070 | — |
| 반응물 | HCID 178511070 | HCID 178511070 | — |
| 반응물 | HCID 178511200 | HCID 178511200 | — |
| 생성물 | tert-butyl N-(1-cyanocyclopropyl)carbamate | HCID 20825555 | — |
반응 단계
The following compounds were prepared using similar procedures as described above: 3,N-Dihydroxy-propionamidine, N-Hydroxy-propionamidine, 3,3,3-Trifluoro-N-hydroxy-propionamidine, N-Hydroxy-dimethylamine-1-carboxamidine, [1-(N-Hydroxy-carbamimidoyl)-cyclopropyl]-carbamic acid tert-butyl ester; (1-Cyano-cyclopropyl)-carbamic acid tert-butyl ester was prepared from 1-tert-butoxycarbonylamino-cyclopropanecarboxylic acid according to literature procedures (Demko, Z. P.; Sharpless, K. B. Org. Lett. 2002, 4, 2525).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08552205B2 |
| 출처 데이터셋 | uspto-grants-2013_10 |
| ORD ID | ord-ab3ce088ae114c7b892d7bfb681fbaa2 |
| 출처 메모 | uspto-grants-2013_10 |