4-Nitroindan → 4-Aminoindan

HRID 1042359

반응식

HRID 1042359 반응식
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH2:6][CH2:7][CH2:8]2)([O-])=O>CO.[Pd]>[CH2:8]1[C:9]2[C:5](=[C:4]([NH2:1])[CH:12]=[CH:11][CH:10]=2)[CH2:6][CH2:7]1

참가 물질

4

반응물 1

HCID 2535784-Nitroindan

생성물 1

HCID 1225694-Aminoindan

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

4-Nitro-indan (5.00 g, 30.70 mmol) was dissolved in methanol, and Pd/C (500 mg) was added. The resulting reaction mixture was hydrogenated at 50 psi for 14 hours. Filtration through celite and concentration afforded the title indan-4-yl-amine.

후처리

  1. customThe resulting reaction mixture
  2. filtrationFiltration
  3. concentrationthrough celite and concentration

출처 및 근거

ORD 기록
ord-188263aad68d460089858ec4f2183d14
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08557853B2

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