Aluminium lithium hydride → 2-Ethoxy-4-(trifluoromethyl)benzaldehyde

HRID 1042458노트

반응식

HRID 1042458 반응식
CON(C)[C:4](=[O:18])[C:5]1[CH:10]=[CH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[CH:7][C:6]=1[O:15][CH2:16][CH3:17].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH2:16]([O:15][C:6]1[CH:7]=[C:8]([C:11]([F:12])([F:13])[F:14])[CH:9]=[CH:10][C:5]=1[CH:4]=[O:18])[CH3:17]

참가 물질

3

반응물 2

HCID 21226445Aluminium lithium hydrideHCID 86649957N-methoxy-N-methyl-2-ethoxy-4-trifluoromethyl-benzamide

생성물 1

HCID 224943382-Ethoxy-4-(trifluoromethyl)benzaldehyde수율 89.1%

실험 절차

N-Methoxy-N-methyl-2-ethoxy-4-trifluoromethyl-benzamide (1.04 g) was reacted with 1 M LAH (1 ml) at −40° C. for 2 hrs as described above to yield title compound (729 mg, 65%)

출처 및 근거

ORD 기록
ord-c2788596af4a4dd391b226db3bbe9fb4
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08557872B2

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