Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyanuric chloride → Tert-butyl ((2r,5s,7as)-5-cyano-3-oxohexahydropyrrolizin-2-yl)carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyanuric chloride | HCID 7954 | — |
| 반응물 | Tert-butyl ((2r,5s,7as)-5-carbamoyl-3-oxohexahydropyrrolizin-2-yl)carbamate | HCID 90895673 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Tert-butyl ((2r,5s,7as)-5-cyano-3-oxohexahydropyrrolizin-2-yl)carbamate | HCID 91321587 | — |
반응 단계
100 mg of tert-butyl ((2R,5S,7aS)-5-carbamoyl-3-oxohexahydropyrrolizin-2-yl)carbamate were dissolved in 2 ml of dimethylformamide, and 65 mg of cyanuric chloride were added. The mixture was stirred for 3 h, and the dimethylformamide was removed in vacuo. The residue was chromatographed on silica gel.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07094800B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-93eff2bf0daa450c897e724582f37625 |
| 출처 메모 | uspto-grants-2006_08 |