Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → (3s,6r,7As)-6-amino-5-oxohexahydropyrrolizine-3-carbonitrile trifluoroacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Thioanisole | HCID 7520 | — |
| 반응물 | Tert-butyl ((2r,5s,7as)-5-cyano-3-oxohexahydropyrrolizin-2-yl)carbamate | HCID 91321587 | — |
| 생성물 | (3s,6r,7As)-6-amino-5-oxohexahydropyrrolizine-3-carbonitrile trifluoroacetate | HCID 11357934 | — |
반응 단계
80 mg of tert-butyl ((2R,5S,7aS)-5-cyano-3-oxohexahydropyrrolizin-2-yl)carbamate were C reacted with 10% thioanisole in 1 ml of trifluoroacetic acid for 30 min. The solvents were then removed in vacuo, and the residue was stirred with diusopropyl ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07094800B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-300496268f1a4ca7a2622d242dab1799 |
| 출처 메모 | uspto-grants-2006_08 |