Hexane → HCID 178516446, 화합물

HRID 1042846노트

반응식

HRID 1042846 반응식
CC1(C)O[C:6](=[O:8])[C:5](=[CH:9][NH:10][C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)C(=O)O1.CCCCCC>C1(OC2C=CC=CC=2)C=CC=CC=1>[N:10]1[C:11]2[C:12](=[CH:13][N:14]=[CH:15][CH:16]=2)[C:6]([OH:8])=[CH:5][CH:9]=1

참가 물질

4

반응물 2

HCID 8058HexaneHCID 59427333HCID 59427333, 화합물

생성물 1

HCID 178516446HCID 178516446, 화합물

시약·촉매·용매 1

HCID 7583Diphenyl Ether용매

실험 절차

A solution of 2,2-dimethyl-5-((pyridin-4-ylamino)methylene)-1,3-dioxane-4,6-dione (1.149 g, 4.63 mmol) in diphenyl ether was heated at 200° C. for 20 min, then cooled to RT. Hexane was added and the mixture was stirred at RT for 30 mins. The solid was filtered off and washed with hexane to furnish 1,6-naphthyridin-4-ol as an off-brown solid.

후처리

  1. filtrationThe solid was filtered off
  2. washwashed with hexane

출처 및 근거

ORD 기록
ord-953f7361ca1e44479d026f55ba6dd1e9
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08557816B2

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