Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Hydroxybenzaldehyde → 3-(Dimethylaminomethyl)phenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Hydroxybenzaldehyde | HCID 101 | — |
| 반응물 | Dimethylamine | HCID 674 | — |
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Sodium triacetoxyborohydride | HCID 5049666 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-(Dimethylaminomethyl)phenol | HCID 32896 | — |
반응 단계
3-Hydroxybenzaldehyde (1.0 g), 2M dimethylamine in THF (5 mL), and sodium triacetoxyborohydride (2 g) in CH2Cl2 (10 mL) were stirred for 24 hours. The mixture was treated with methanol and chromatographed on silica gel with 2-25% ethyl acetate/hexanes.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08557983B2 |
| 출처 데이터셋 | uspto-grants-2013_10 |
| ORD ID | ord-a87bbf9c63684d14a3aff343df0d7a24 |
| 출처 메모 | uspto-grants-2013_10 |