tert-Butyl carbazate → tert-butyl 2-(dihydrofuran-3(2H)-ylidene)hydrazinecarboxylate
반응식
O=[C:2]1[CH2:6][CH2:5][O:4][CH2:3]1.[C:7]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])(=[O:10])[NH:8][NH2:9]>CO>[O:4]1[CH2:5][CH2:6][C:2](=[N:9][NH:8][C:7]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10])[CH2:3]1참가 물질
4
실험 절차
3-oxotetrahydrofuran (10.38 g) was dissolved in methanol (200 mL), and t-butyl carbazate (17.53 g) was added to the solution. The mixture was stirred at room temperature for 12 hours. The reaction mixture was concentrated to give the title compound (27.3 g). 1H-NMR (400 MHz, CDCl3) δ (ppm): 1.52 (s, 9H), 2.46 (t, J=6.9 Hz, al), 4.10 (t, J=6.9 Hz, 2H), 4.33 (s, 2H).
후처리
- concentrationThe reaction mixture was concentrated
출처 및 근거
- ORD 기록
- ord-23a8f39bfbf64426b5f81b0a33ecfbdb
- 출처 데이터셋
- uspto-grants-2013_10
- 특허 번호
- US08563565B2
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