1,4-Dioxane hydrochloride → (3SR,4RS)-4-hydrazinyltetrahydrofuran-3-ol hydrochloride

HRID 1043885

반응식

HRID 1043885 반응식
O1CCOCC1.[ClH:7].[OH:8][CH:9]1[CH2:13][O:12][CH2:11][CH:10]1[NH:14][NH:15]C(OC(C)(C)C)=O>CO>[ClH:7].[NH:14]([CH:10]1[CH2:11][O:12][CH2:13][CH:9]1[OH:8])[NH2:15]

참가 물질

4

반응물 2

HCID 204431481,4-Dioxane hydrochlorideHCID 86686323t-butyl 2-((3RS,4SR)-4-hydroxytetrahydrofuran-3-yl)hydrazinecarboxylate

생성물 1

HCID 86686324(3SR,4RS)-4-hydrazinyltetrahydrofuran-3-ol hydrochloride

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A 4 M hydrogen chloride-1,4-dioxane solution (50 mL) was added to a solution of t-butyl 2-((3RS,4SR)-4-hydroxytetrahydrofuran-3-yl)hydrazinecarboxylate (5.78 g) in methanol (30 mL) under ice-cooling, and the mixture was then warmed to room temperature and stirred overnight. The reaction mixture was concentrated to give the title compound (5 g).

후처리

  1. temperaturecooling
  2. concentrationThe reaction mixture was concentrated

출처 및 근거

ORD 기록
ord-2a0fc353c9dd48bfa2d7ccc7df69d076
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08563565B2

연결된 노트

불러오는 중…