Nitrogen → 5-Nitro-2-pentanone

HRID 1044731노트

반응식

HRID 1044731 반응식
N#N.[CH:3]([C:5]([CH3:7])=[O:6])=[CH2:4].[N+:8]([CH3:11])([O-:10])=[O:9]>>[N+:8]([CH2:11][CH2:4][CH2:3][C:5](=[O:6])[CH3:7])([O-:10])=[O:9]

참가 물질

4

반응물 3

HCID 947NitrogenHCID 6375NitromethaneHCID 6570Methyl vinyl ketone

생성물 1

HCID 42950035-Nitro-2-pentanone

실험 절차

In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), to a solution of methyl vinyl ketone (2.32 mL, 28.53 mmol) in nitromethane (29.6 mL) was added activated KF/Al2O3 (323 mg, prepared by mixing KF and basic Al2O3 in water followed by concentrating and drying) at 0° C. The reaction mixture was then allowed to warm up to rt and stirred at this temperature for 18 h. The mixture was filtered through neutral Al2O3 and washed with CH2Cl2. The filtrated was concentrated under reduced pressure to give the title compound as a colorless oil.

후처리

  1. additionwas added
  2. customat 0° C
  3. filtrationThe mixture was filtered through neutral Al2O3
  4. washwashed with CH2Cl2
  5. concentrationThe filtrated was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-0d2573c018274854b4e6e64fdc1082d6
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08563714B2

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