Benzyl 3-(3-hydroxypropyl)piperidine-1-carboxylate → Benzyl 3-(3-bromopropyl)piperidine-1-carboxylate

HRID 1044882노트

반응식

HRID 1044882 반응식
[Br:1]CCCC1CCCCN1C(OCC1C=CC=CC=1)=O.O[CH2:22][CH2:23][CH2:24][CH:25]1[CH2:30][CH2:29][CH2:28][N:27]([C:31]([O:33][CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)=[O:32])[CH2:26]1>>[Br:1][CH2:22][CH2:23][CH2:24][CH:25]1[CH2:30][CH2:29][CH2:28][N:27]([C:31]([O:33][CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)=[O:32])[CH2:26]1

참가 물질

3

반응물 2

HCID 58306111Benzyl 3-(3-hydroxypropyl)piperidine-1-carboxylateHCID 58306190Benzyl 2-(3-bromopropyl)piperidine-1-carboxylate

생성물 1

HCID 58306103Benzyl 3-(3-bromopropyl)piperidine-1-carboxylate

실험 절차

Prepared similarly to Intermediate 30 from phenylmethyl 3-(3-hydroxypropyl)-1-piperidinecarboxylate.

출처 및 근거

ORD 기록
ord-2eeb920d83274eff888304917f758a3d
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08563717B2

반응 노트

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