5-(1-Benzyloxycarbonyl-4-piperidyl)pentanol → Phenylmethyl 4-(5-bromopentyl)-1-piperidinecarboxylate

반응식

[Br:1]CCCC1CCCCN1C(OCC1C=CC=CC=1)=O.O[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH:27]1[CH2:32][CH2:31][N:30]([C:33]([O:35][CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)=[O:34])[CH2:29][CH2:28]1>>[Br:1][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH:27]1[CH2:32][CH2:31][N:30]([C:33]([O:35][CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)=[O:34])[CH2:29][CH2:28]1

참가 물질

반응물 2

HCID 140469305-(1-Benzyloxycarbonyl-4-piperidyl)pentanol

HCID 58306190Benzyl 2-(3-bromopropyl)piperidine-1-carboxylate

생성물 1

HCID 58306239Phenylmethyl 4-(5-bromopentyl)-1-piperidinecarboxylate

실험 절차

Prepared similarly to Intermediate 30 from phenylmethyl 4-(5-hydroxypentyl)-1-piperidinecarboxylate.

출처 및 근거

ORD 기록: ord-d6e91c7fd25645da8339c76313c76a0b
출처 데이터셋: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08563717B2

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