HCID 68956549, 화합물 → HCID 68654072, 화합물
반응식
C([O:8][C:9](=[O:26])[CH2:10][C:11]1[CH:12]=[C:13]([CH:23]=[CH:24][CH:25]=1)[O:14][CH2:15][CH2:16][CH2:17][C:18]([O:20][CH2:21]C)=[O:19])C1C=CC=CC=1>CO.[Pd]>[CH3:21][O:20][C:18](=[O:19])[CH2:17][CH2:16][CH2:15][O:14][C:13]1[CH:12]=[C:11]([CH2:10][C:9]([OH:26])=[O:8])[CH:25]=[CH:24][CH:23]=1참가 물질
4
실험 절차
The mixture of ethyl 4-(3-(2-(benzyloxy)-2-oxoethyl)phenoxy)butanoate (2.05 g, 5.77 mmol) and Pd/C (0.207 g) in methanol was stirred at room temperature under H2 overnight. The mixture was filtered and the filtrate was concentrated under reduce pressure. The residue was washed with ether, filtrated and dried to obtain 2-(3-(4-methoxy-4-oxobutoxy)phenyl)acetic acid (compound 0202-35) (1 g, 66%): LCMS: 267 [M+1]+.
후처리
- filtrationThe mixture was filtered
- concentrationthe filtrate was concentrated
- washThe residue was washed with ether
- filtrationfiltrated
- customdried
출처 및 근거
- ORD 기록
- ord-32ff7247a0854a389a7a3231a183426d
- 출처 데이터셋
- uspto-grants-2013_10
- 특허 번호
- US08563741B2
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