2-Bromo-2-methylpropionyl bromide → HCID 67411846, 화합물

HRID 1045391

반응식

HRID 1045391 반응식
[NH2:1][C:2]1[S:3][CH:4]=[CH:5][C:6]=1[C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[H][H].[Br:17][C:18]([CH3:23])([CH3:22])[C:19](Br)=[O:20]>>[C:7]([C:6]1[CH:5]=[CH:4][S:3][C:2]=1[NH:1][C:19](=[O:20])[C:18]([Br:17])([CH3:23])[CH3:22])(=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

4

반응물 3

HCID 886852-Bromo-2-methylpropionyl bromideHCID 644720(2-Aminothiophen-3-yl)(phenyl)methanoneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 67411846HCID 67411846, 화합물수율 86%

실험 절차

1.0 g 2-Amino-3-benzoyl-thiophene (compound 3 wherein R3 is hydrogen) was acylated with 2-bromo-2-methylpropanoyl bromide to give 1.49 g (86%) of the title compound.

출처 및 근거

ORD 기록
ord-da0969570dee4fb5b405e6874ff4eff7
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08569288B2

연결된 노트

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