2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol → 2-[[2-[[1-(2-hydroxyethyl)-3-methyl-pyrazol-4-yl]amino]-5-(trifluoromethyl)-4-pyridyl]amino]-N-methyl-benzamide

HRID 1045970노트

반응식

HRID 1045970 반응식
Cl[C:2]1[CH:7]=[C:6]([NH:8][C:9]2[CH:18]=[CH:17][CH:16]=[CH:15][C:10]=2[C:11]([NH:13][CH3:14])=[O:12])[C:5]([C:19]([F:22])([F:21])[F:20])=[CH:4][N:3]=1.[NH2:23][C:24]1[C:25]([CH3:32])=[N:26][N:27]([CH2:29][CH2:30][OH:31])[CH:28]=1>>[OH:31][CH2:30][CH2:29][N:27]1[CH:28]=[C:24]([NH:23][C:2]2[CH:7]=[C:6]([NH:8][C:9]3[CH:18]=[CH:17][CH:16]=[CH:15][C:10]=3[C:11]([NH:13][CH3:14])=[O:12])[C:5]([C:19]([F:22])([F:21])[F:20])=[CH:4][N:3]=2)[C:25]([CH3:32])=[N:26]1

참가 물질

3

반응물 2

HCID 552846902-(4-Amino-3-methyl-pyrazol-1-yl)-ethanolHCID 566553282-[2-Chloro-5-(trifluoromethyl)pyridin-4-ylamino]-N-methylbenzamide

생성물 1

HCID 583365962-[[2-[[1-(2-hydroxyethyl)-3-methyl-pyrazol-4-yl]amino]-5-(trifluoromethyl)-4-pyridyl]amino]-N-methyl-benzamide

실험 절차

This compound was prepared from 2-[[2-chloro-5-(trifluoromethyl)pyridin-4-yl]amino]-N-methylbenzamide and 2-(4-amino-3-methyl-pyrazol-1-yl)ethanol.

출처 및 근거

ORD 기록
ord-e4550c126c244f509b07a01bf0991365
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08569298B2

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