2-amino-4-fluoro-N-methylbenzamide → 2-[[2-[(2,5-dimethylpyrazol-3-yl)amino]-5-(trifluoromethyl)-4-pyridyl]amino]-4-fluoro-N-methyl-benzamide

참여 물질

역할	이름	HCID	투입량
반응물	2-amino-4-fluoro-N-methylbenzamide	HCID 56951661	—
반응물	N-(1,3-dimethylpyrazol-5-yl)-4-iodo-5-(trifluoromethyl)pyridin-2-amine	HCID 67075489	—
생성물	2-[[2-[(2,5-dimethylpyrazol-3-yl)amino]-5-(trifluoromethyl)-4-pyridyl]amino]-4-fluoro-N-methyl-benzamide	HCID 56951292	—

반응 단계

This compound was prepared from N-(1,3-dimethylpyrazol-5-yl)-4-iodo-5-(trifluoromethyl)pyridin-2-amine and 2-amino-4-fluoro-N-methylbenzamide. 54 mg, 33%; triturated in tBuOMe; NMR Spectrum: (DMSOd6) 2.08 (s, 3H), 2.76 (d, 3H), 3.55 (s, 3H), 6.04 (s, 1H), 6.76 (s, 1H), 6.95 (ddd, 1H), 7.39 (dd, 1H), 7.79 (dd, 1H), 8.27 (s, 1H), 8.69 (q, 1H), 9.06 (s, 1H), 10.65 (s, 1H); Mass spectrum: MH+ 423.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08569298B2
출처 데이터셋	uspto-grants-2013_10
ORD ID	ord-f34f1c4b4a424d1e83c8152bebd7c626
출처 메모	uspto-grants-2013_10