Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → Lamivudine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Lamivudine oxalate | HCID 86677229 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | Lamivudine | HCID 60825 | — |
반응 단계
Specifically, Lamivudine oxalate is added to ethanol, and an amount of triethylamine is added thereto at the temperature of 40˜45° C. for 0.5 hr, and stirred for 4 h at the same temperature. The mixture is centrifuged at room temperature, and a product is dried under vacuum at the temperature of 40˜45° C. to obtain Lamivudine crystal.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08569322B2 |
| 출처 데이터셋 | uspto-grants-2013_10 |
| ORD ID | ord-eb7e2ad85efd4d20b3416678baf39123 |
| 출처 메모 | uspto-grants-2013_10 |