Nitric Acid → Norvaline Dinitrate

HRID 1046719

반응식

HRID 1046719 반응식
[N+:1]([O-:4])([OH:3])=[O:2].[NH2:5][C@H:6]([C:10]([OH:12])=[O:11])[CH2:7][CH2:8][CH3:9].[N+:13]([O-:16])([OH:15])=[O:14].[NH2:17][C@H:18]([C:22]([OH:24])=[O:23])[CH2:19][CH2:20][CH3:21]>O>[N+:1]([O-:4])([OH:3])=[O:2].[N+:13]([O-:16])([OH:15])=[O:14].[NH2:5][C@H:6]([C:10]([OH:12])=[O:11])[CH2:7][CH2:8][CH3:9].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[NH2:17][C@H:18]([C:22]([OH:24])=[O:23])[CH2:19][CH2:20][CH3:21]

참가 물질

6

반응물 3

HCID 944Nitric AcidHCID 65098L-NorvalineHCID 86628854HCID 86628854, 화합물

생성물 2

HCID 86628852Norvaline DinitrateHCID 86628853Norvaline Trinitrate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Applicants have cost-effectively synthesized Norvaline Nitrate by combining nitric acid and Norvaline, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Norvaline Dinitrate or Norvaline Trinitrate. An alternative implementation comprises substituting Nitrous Acid (HNO2) for Nitric Acid (HNO3), thus yielding Norvaline Nitrite. Norvaline Nitrite has the same effects as Norvaline Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Norvaline Nitrate-Orotate.

후처리

  1. customleaving
  2. customto crystallize

출처 및 근거

ORD 기록
ord-e2447ebd61824732b11dd5c1c13e1c4b
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08569369B2

연결된 노트

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