Aminoacetaldehyde dimethyl acetal → HCID 178495885, 화합물

HRID 1046991노트

반응식

HRID 1046991 반응식
[N:1]1[C:6]2[NH:7][C:8]3[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=3[C:10](=S)[NH:11][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH3:17][O:18][CH:19]([O:22][CH3:23])[CH2:20][NH2:21]>>[CH3:17][O:18][CH:19]([O:22][CH3:23])[CH2:20][NH:21][C:10]1[C:9]2[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=2[NH:7][C:6]2[N:1]=[CH:2][CH:3]=[CH:4][C:5]=2[N:11]=1

참가 물질

3

반응물 2

HCID 89728Aminoacetaldehyde dimethyl acetalHCID 454962295,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-thione

생성물 1

HCID 178495885HCID 178495885, 화합물

반응 조건

온도
95 °C

실험 절차

A mixture of 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-thione (3.21 g, 14 mmol) and 2,2-dimethoxyethylamine (7.6 mL, 70 mmol) was heated to 95° C. for 1 hour. After cooling to room temperature the solvent was evaporated in vacuo. The crude product was used in the next step without further purification.

후처리

  1. temperatureAfter cooling to room temperature the solvent
  2. customwas evaporated in vacuo
  3. customThe crude product was used in the next step without further purification

출처 및 근거

ORD 기록
ord-1ddb5d730f7a48b5a2e2bc5cae496d22
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08569331B2

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