Hydrazine → HCID 178419360, 화합물

HRID 1047308노트

반응식

HRID 1047308 반응식
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8](/[N:10]=[CH:11]/[N:12](C)C)=O)=[N:6][CH:7]=1.[NH2:15]N>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:10]=[CH:11][NH:12][N:15]=2)=[N:6][CH:7]=1

참가 물질

3

반응물 2

HCID 9321HydrazineHCID 178484325HCID 178484325, 화합물

생성물 1

HCID 178419360HCID 178419360, 화합물수율 83.2%

실험 절차

A solution of (E)-5-bromo-N-((dimethylamino)methylene)picolinamide (0.604 mg, 2.36 mmol) and hydrazine (2.12 g, 66.1 mmol) was stirred at 25° C. for 3 h. The reaction was concentrated and diluted with water. The resulting precipitate was collected by filtration and dried under vacuum to give the title compound (0.442 g, 83% yield). MS (ESI) m/z 226.1 [M+1]+.

후처리

  1. concentrationThe reaction was concentrated
  2. additiondiluted with water
  3. filtrationThe resulting precipitate was collected by filtration
  4. customdried under vacuum

출처 및 근거

ORD 기록
ord-9739db0a692c4a26bfc27edd644843b1
출처 데이터셋
uspto-grants-2013_10
특허 번호
US08569494B2

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