3,6-Difluorophthalic acid → 2-Amino-4,7-difluoro-indan-2-carboxylic acid ethyl ester HCl salt
반응식
[F:1][C:2]1[CH:10]=[CH:9][C:8]([F:11])=[C:4]([C:5](O)=O)[C:3]=1[C:12](O)=O.[ClH:15].[CH2:16]([O:18][C:19]([C:21]1([NH2:32])CC2C(=CC=C(F)C=2F)C1)=[O:20])[CH3:17]>>[ClH:15].[CH2:16]([O:18][C:19]([C:21]1([NH2:32])[CH2:5][C:4]2[C:3](=[C:2]([F:1])[CH:10]=[CH:9][C:8]=2[F:11])[CH2:12]1)=[O:20])[CH3:17]참가 물질
3
실험 절차
2-Amino-4,7-difluoro-indan-2-carboxylic acid ethyl ester HCl salt was prepared from 3,6-difluoro-phthalic acid as indicated by the scheme above regarding A7-D7 utilizing the same procedures as for the synthesis of 2-amino-4,5-difluoro-indan-2-carboxylic acid ethyl ester HCl salt.
출처 및 근거
- ORD 기록
- ord-316a2a5446b74a879cbd8e1e5eac5830
- 출처 데이터셋
- uspto-grants-2013_10
- 특허 번호
- US08569535B2
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