2,3-Dihydroxybutanedioic Acid → Apomorphine

HRID 1048684

반응식

HRID 1048684 반응식
[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1.O.[C:22]([OH:31])(=[O:30])[CH:23]([CH:25]([C:27]([OH:29])=[O:28])[OH:26])[OH:24]>>[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1.[C:27]([CH:25]([CH:23]([C:22]([O-:31])=[O:30])[OH:24])[OH:26])([O-:29])=[O:28].[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1

참가 물질

5

반응물 3

HCID 8752,3-Dihydroxybutanedioic AcidHCID 962WaterHCID 6005Apomorphine

생성물 2

HCID 6005ApomorphineHCID 131735990Apomorphine tartrate

실험 절차

Apomorphine tartrate solution was prepared by dissolving apomorphine base in 0.1M tartaric acid solution. Water was added to obtain solutions with a molar ratio of 1:1 or 1:0.5, apomorphine:tartaric acid, at a concentration of 2% apomorphine. The pH of each solution was 3.45 and 4.0, respectively.

출처 및 근거

ORD 기록
ord-27c2528296b349b5aeccb433aa04c495
출처 데이터셋
uspto-grants-2016_07
특허 번호
US09381249B2

연결된 노트

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